Pathway-focused gRNA文库是靶向筛选特定通路的理想工具。使用经由药物基因交互数据库确定的基因靶点，设计好的文库可用于通路或疾病相关基因的筛选。所有gRNA序列由Broad研究所预先设计和验证，并克隆至pLentiCRISPR v2载体中。交付的文库为转染级，可用于慢病毒包装。
pathway-focused文库可交付转染级，或者提供包装后的慢病毒工作液。
pathway-focused library list
| Catalog # | Pathway | Gene # | gRNA # | Quantity |
| HKC0282-25 | ABC Transporter | 100 | 298 | 25 μg |
| HKC0282-100 | 100 μg |
| HKC0283-25 | Adult Stem Cells | 58 | 174 | 25 μg |
| HKC0283-100 | 100 μg |
| HKC0284-25 | Angiogenesis | 92 | 276 | 25 μg |
| HKC0284-100 | 100 μg |
| HKC0285-25 | Apoptosis | 68 | 204 | 25 μg |
| HKC0285-100 | 100 μg |
| HKC0286-25 | cAMP & calcium Signaling Pathway | 91 | 271 | 25 μg |
| HKC0286-100 | 100 μg |
| HKC0287-25 | Cell Cycle | 84 | 252 | 25 μg |
| HKC0287-100 | 100 μg |
| HKC0288-25 | Cytochrome P450 | 57 | 171 | 25 μg |
| HKC0288-100 | 100 μg |
| HKC0289-25 | Drug Resistance | 348 | 1044 | 25 μg |
| HKC0289-100 | 100 μg |
| SC1830-25 | GPCR | 280 | 840 | 25 μg |
| SC1830-100 | 100 μg |
| SC1834-25 | Hormone Activity | 108 | 324 | 25 μg |
| SC1834-100 | 100 μg |
| SC1836-25 | Ion Channels (Potassium) | 67 | 201 | 25 μg |
| SC1836-100 | 100 μg |
| SC1837-25 | Tumor Metastasis | 60 | 180 | 25 μg |
| SC1837-100 | 100 μg |
